O-17:over the edge 疯了
A:I hear that Mary got mad.
A:我听说玛丽疯了。
B:So I heard.
B:我也听说了。
A:What's wrong with her?
A:怎么搞的?
B:She went over the edge after her son was killed in an accident.
B:自从他儿子在一次车祸中丧生后,她就疯了。